Anti-HAL Antibody Picoband®

About this product

Boster Bio Anti-HAL Antibody Picoband® catalog # A02612-1. Tested in WB, IHC, IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A02612-1-carrier-free

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Histidine ammonia-lyase is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. Histidine ammonia-lyase defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids. Several transcript variants encoding different isoforms have been found for this gene.

Synonyms

HAL; HIS; Histidine ammonia-lyase; Histidase; EC 4.3.1.3

Gene Name

HAL

Gene ID

3034

UniProt

P42357

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human HAL recombinant protein (Position: D65-R632) . Human HALshares 95.2% and 95.4% amino acid (aa) sequence identity with mouse and rat HAL, respectively.

Clonality

Polyclonal

Applications

WB, IHC, IF, Flow Cytometry, ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Kacser, H. K., Bulfield, G., Wallace, M. E. Histidinaemia mutant in the mouse. Nature 244: 77-79, 1973. 2. Kanarek, N., Keys, H. R., Cantor, J. R., Lewis, C. A., Chan, S. H., Kunchok, T., Abu-Remaileh, M., Freinkman, E., Schweitzer, L. D., Sabatini, D. M. Histidine catabolism is a major determinant of methotrexate sensitivity. Nature 559: 632-636, 2018. Note: Erratum: Nature 602: E17-E18, 2022. 3. Kawai, Y., Moriyama, A., Asai, K., Coleman-Campbell, C. M., Sumi, S., Morishita, H., Suchi, M. Molecular characterization of histidinemia: identification of four missense mutations in the histidase gene. Hum. Genet. 116: 340-346, 2005. Note: Erratum: Hum. Genet. 118: 531-532, 2005.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

73 kDa

Observed Molecular Weight

75 kDa

Applications Notes

6

Gene Name Synonym

Histidine ammonia-lyase

Protein Name

Histidine ammonia-lyase

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.