Anti-MCAT Antibody Picoband®

About this product

Boster Bio Anti-MCAT Antibody Picoband® catalog # A04806-1. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A04806-1-carrier-free

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

The protein encoded by this gene is found exclusively in the mitochondrion, where it catalyzes the transfer of a malonyl group from malonyl-CoA to the mitochondrial acyl carrier protein. The encoded protein may be part of a fatty acid synthase complex that is more like the type II prokaryotic and plastid complexes rather than the type I human cytosolic complex. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms

MCAT; MT; Malonyl-CoA-acyl carrier protein transacylase, mitochondrial; MCT; EC 2.3.1.39; Mitochondrial malonyl CoA:ACP acyltransferase; Mitochondrial malonyltransferase; [Acyl-carrier-protein] malonyltransferase

Gene Name

MCAT

Gene ID

7349

UniProt

Q8IVS2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human MCAT recombinant protein (Position: E37-R390) .

Clonality

Polyclonal

Applications

WB, IHC, ICC/IF, IP, Flow Cytometry, ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Gerber, S., Orssaud, C., Kaplan, J., Johansson, C., Rozet, J. M. MCAT mutations cause nuclear LHON-like optic neuropathy. Genes 12: 521, 2021. 2. Li, H., Yuan, S., Minegishi, Y., Suga, A., Yoshitake, K., Sheng, X., Ye, J., Smith, S., Bunkoczi, G., Yamamoto, M., Iwata, T. Novel mutations in malonyl-CoA-acyl carrier protein transacylase provoke autosomal recessive optic neuropathy. Hum. Molec. Genet. 29: 444-458, 2020. 3. Webb, B. D., Nowinski, S. M., Solmonson, A., Ganesh, J., Rodenburg, R. J., Leandro, J., Evans, A., Vu, H. S., Naidich, T. P., Gelb, B. D., DeBerardinis, R. J., Rutter, J., Houten, S. M. Recessive pathogenic variants in MCAT cause combined oxidative phosphorylation deficiency. eLife 12: e68047, 2023.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

43 kDa

Observed Molecular Weight

39 kDa

Applications Notes

6

Gene Name Synonym

Malonyl-CoA-acyl carrier protein transacylase

Protein Name

Malonyl-CoA-acyl carrier protein transacylase, mitochondrial

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.