Anti-NKX3-1 Antibody Picoband®

About this product

Boster Bio Anti-NKX3-1 Antibody Picoband® catalog # A02709-5. Tested in WB, Flow Cytometry applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A02709-5

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

This gene encodes a homeobox-containing transcription factor. This transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of this gene is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of this gene.

Synonyms

Nkx3-1; Nkx-3.1; Nkx3a; Homeobox protein Nkx-3.1; Homeobox protein NK-3 homolog A

Gene Name

NKX3-1

Gene ID

18095

UniProt

P97436

Host

Rabbit

Reactivity

Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of mouse NKX3-1. Mouse NKX3-1 shares 80% amino acid (aa) sequence identity with human NKX3-1.

Clonality

Polyclonal

Applications

WB, Flow Cytometry

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Abdulkadir, S. A., Magee, J. A., Peters, T. J., Kaleem, Z., Naughton, C. K., Humphrey, P. A., Milbrandt, J. Conditional loss of Nkx3.1 in adult mice induces prostatic intraepithelial neoplasia. Molec. Cell. Biol. 22: 1495-1503, 2002. 2. Bieberich, C. J., Fujita, K., He, W. W., Jay, G. Prostate-specific and androgen-dependent expression of a novel homeobox gene. J. Biol. Chem. 271: 31779-31782, 1996. 3. Dutta, A., Le Magnen, C., Mitrofanova, A., Ouyang, X., Califano, A., Abate-Shen, C. Identification of an NKX3.1-G9a-UTY transcriptional regulatory network that controls prostate differentiation. Science 352: 1576-1580, 2016.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

26 kDa

Observed Molecular Weight

36 kDa

Applications Notes

6

Gene Name Synonym

NK3 homeobox 1

Protein Name

Homeobox protein Nkx-3.1

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.