Anti-FHOD1 Antibody Picoband®

About this product

Boster Bio Anti-FHOD1 Antibody Picoband® catalog # A07228-1. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A07228-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

This gene encodes a protein which is a member of the formin/diaphanous family of proteins. The gene is ubiquitously expressed but is found in abundance in the spleen. The encoded protein has sequence homology to diaphanous and formin proteins within the Formin Homology (FH) 1 and FH2 domains. It also contains a coiled-coil domain, a collagen-like domain, two nuclear localization signals, and several potential PKC and PKA phosphorylation sites. It is a predominantly cytoplasmic protein and is expressed in a variety of human cell lines. Alternative splicing results in multiple transcript variants.

Synonyms

FHOD1; FHOS; FHOS1; FH1/FH2 domain-containing protein 1; Formin homolog overexpressed in spleen 1; FHOS; Formin homology 2 domain-containing protein 1

Gene Name

FHOD1

Gene ID

29109

UniProt

Q9Y613

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human FHOD1 recombinant protein (Position: D290-R1121) . Human FHOD1 shares 82.2% amino acid (aa) sequence identity with mouse FHOD1.

Clonality

Polyclonal

Applications

WB, Flow Cytometry, ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Sanematsu, F., Kanai, A., Ushijima, T., Shiraishi, A., Abe, T., Kage, Y., Sumimoto, H., Takeya, R. Fhod1, an actin-organizing formin family protein, is dispensable for cardiac development and function in mice. Cytoskeleton 76: 219-229, 2019. 2. Westendorf, J. J., Koka, S. Identification of FHOD1-binding proteins and mechanisms of FHOD1-regulated actin dynamics. J. Cell. Biochem. 92: 29-41, 2004. 3. Westendorf, J. J., Mernaugh, R., Hiebert, S. W. Identification and characterization of a protein containing formin homology (FH1/FH2) domains Gene 232: 173-182, 1999.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

127 kDa

Observed Molecular Weight

140 kDa

Applications Notes

6

Gene Name Synonym

Formin homology 2 domain containing 1

Protein Name

FH1/FH2 domain-containing protein 1

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.