Anti-NRCAM Antibody Picoband®

About this product

Boster Bio Anti-NRCAM Antibody Picoband® catalog # A03746-1. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A03746-1-carrier-free

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Enables protein binding activity involved in heterotypic cell-cell adhesion. Involved in cell-cell adhesion; nervous system development; and regulation of postsynapse organization. Acts upstream of or within several processes, including neuron development; neuronal action potential propagation; and regulation of neuron projection development. Located in axon; plasma membrane; and synapse. Is active in glutamatergic synapse and postsynaptic density membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Used to study autism spectrum disorder. Orthologous to human NRCAM (neuronal cell adhesion molecule) .

Synonyms

Nrcam; Kiaa0343; Neuronal cell adhesion molecule; Nr-CAM; Neuronal surface protein Bravo; mBravo; NgCAM-related cell adhesion molecule; Ng-CAM-related

Gene Name

NRCAM

Gene ID

319504

UniProt

Q810U4

Host

Rabbit

Reactivity

Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human NRCAM recombinant protein (Position: R207-Q1025) . Mouse NRCAM shares 91.7% and 97.1% amino acid (aa) sequence identity with human and rat NRCAM, respectively.

Clonality

Polyclonal

Applications

WB, Flow Cytometry, ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Custer, A. W., Kazarinova-Noyes, K., Sakurai, T., Xu, X., Simon, W., Grumet, M., Shrager, P. The role of the ankyrin-binding protein NrCAM in node of Ranvier formation. J. Neurosci. 23: 10032-10039, 2003. 2. Demyanenko, G. P., Mohan, V., Zhang, X., Brennaman, L. H., Dharbal, K. E. S., Tran, T. S., Manis, P. B., Maness, P. F. Neural cell adhesion molecule NrCAM regulates semaphorin 3F-induced dendritic spine remodeling. J. Neurosci. 34: 11274-11287, 2014. 3. Dry, K., Kenwrick, S., Rosenthal, A., Platzer, M. The complete sequence of the human locus for NgCAM-related cell adhesion molecule reveals a novel alternative exon in chick and man and conserved genomic organization for the L1 subfamily. Gene 273: 115-122, 2001.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

144 kDa

Observed Molecular Weight

136 kDa

Applications Notes

6

Gene Name Synonym

Neuronal cell adhesion molecule

Protein Name

Neuronal cell adhesion molecule

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.