Anti-CHP1 Antibody Picoband®

About this product

Boster Bio Anti-CHP1 Antibody Picoband® catalog # A04737-3. Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A04737-3

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

This gene encodes a phosphoprotein that binds to the Na+/H+ exchanger NHE1. This protein serves as an essential cofactor which supports the physiological activity of NHE family members and may play a role in the mitogenic regulation of NHE1. The protein shares similarity with calcineurin B and calmodulin and it is also known to be an endogenous inhibitor of calcineurin activity.

Synonyms

CHP1; CHP; Calcineurin B homologous protein 1; Calcineurin B-like protein; Calcium-binding protein CHP; Calcium-binding protein p22; EF-hand calcium-binding domain-containing protein p22

Gene Name

CHP1

Gene ID

11261

UniProt

Q99653

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human CHP1. Human CHP1 shares 100% amino acid (aa) sequence identity with both mouse and rat CHP1.

Clonality

Polyclonal

Applications

WB, ICC/IF, Flow Cytometry

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Lin, X., Barber, D. L. A calcineurin homologous protein inhibits GTPase-stimulated Na-H exchange. Proc. Nat. Acad. Sci. 93: 12631-12636, 1996. 2. Lin, X., Sikkink, R. A., Rusnak, F., Barber, D. L. Inhibition of calcineurin phosphatase activity by a calcineurin B homologous protein. J. Biol. Chem. 274: 36125-36131, 1999. 3. Liu, Y., Zaun, H. C., Orlowski, J., Ackerman, S. L. CHP1-mediated NHE1 biosynthetic maturation is required for Purkinje cell axon homeostasis. J. Neurosci. 33: 12656-12669, 2013.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

22 kDa

Observed Molecular Weight

34 kDa

Applications Notes

6

Gene Name Synonym

Calcineurin like EF-hand protein 1

Protein Name

Calcineurin B homologous protein 1

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.