Anti-PGAM5 Antibody Picoband®

About this product

Boster Bio Anti-PGAM5 Antibody Picoband® catalog # A05464. Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A05464

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Enables GTPase activator activity and protein serine/threonine phosphatase activity. Involved in necroptotic process. Located in mitochondrial inner membrane.

Synonyms

PGAM5; Serine/threonine-protein phosphatase PGAM5, mitochondrial; EC 3.1.3.16; Bcl-XL-binding protein v68; Phosphoglycerate mutase family member 5

Gene Name

PGAM5

Gene ID

192111

UniProt

Q96HS1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human PGAM5 recombinant protein (Position: D63-L252) . Human PGAM5 shares 95.3% and 93.7% amino acid (aa) sequence identity with mouse and rat PGAM5, respectively.

Clonality

Polyclonal

Applications

WB, ICC/IF, Flow Cytometry, ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Hartz, P. A. Personal Communication. Baltimore, Md. 10/26/2012. 2. Lo, S.-C., Hannink, M. PGAM5, a Bcl-X-L-interacting protein, is a novel substrate for the redox-regulated Keap1-dependent ubiquitin ligase complex. J. Biol. Chem. 281: 37893-37903, 2006. 3. Sugawara, S., Kanamaru, Y., Sekine, S., Maekawa, L., Takahashi, A., Yamamoto, T., Watanabe, K., Fujisawa, T., Hattori, K., Ichijo, H. The mitochondrial protein PGAM5 suppresses energy consumption in brown adipocytes by repressing expression of uncoupling protein 1. J. Biol. Chem. 295: 5588-5601, 2020.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

32 kDa

Observed Molecular Weight

32 kDa

Applications Notes

6

Gene Name Synonym

PGAM family member 5, mitochondrial serine/threonine protein phosphatase

Protein Name

Serine/threonine-protein phosphatase PGAM5, mitochondrial

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.