Anti-TDP1 Antibody Picoband®

About this product

Boster Bio Anti-TDP1 Antibody Picoband® catalog # A02231-2. Tested in WB, IHC, IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A02231-2

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1) .

Synonyms

TDP1; Tyrosyl-DNA phosphodiesterase 1; Tyr-DNA phosphodiesterase 1; EC 3.1.4.-

Gene Name

TDP1

Gene ID

55775

UniProt

Q9NUW8

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human TDP1 recombinant protein (Position: M1-R499) . Human TDP1 shares 78.8% and 79.6% amino acid (aa) sequence identity with mouse and rat TDP1, respectively.

Clonality

Polyclonal

Applications

WB, IHC, IF, Flow Cytometry, ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

68 kDa

Observed Molecular Weight

70 kDa

Applications Notes

6

Gene Name Synonym

Tyrosyl-DNA phosphodiesterase 1

Protein Name

Tyrosyl-DNA phosphodiesterase 1

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.