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Product details

Anti-TGFB1 Antibody

Catalog number A00019-1-400ul

Price for A00019-1-400ul

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Size / count 400 µL

About this product

Boster Bio Anti-TGFB1 Antibody (Catalog # A00019-1) . Tested in WB application (s) . This antibody reacts with Human, Rat.

Specifications

Catalog number
A00019-1-400ul
Size / count
400 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.
Synonyms
Transforming growth factor beta-1, TGF-beta-1, Latency-associated peptide, LAP, TGFB1, TGFB
Gene Name
TGFB1
UniProt
P01137
Host
Rabbit
Reactivity
Human, Rat
Immunogen
This TGFB1 antibody is generated from a rabbit immunized with a recombinant protein of human TGFB1.
Clonality
Polyclonal
Tissue Specificity
Highly expressed in bone (PubMed:11746498, PubMed:17827158) . Abundantly expressed in articular cartilage and chondrocytes and is increased in osteoarthritis (OA) (PubMed:11746498, PubMed:17827158) . Colocalizes with ASPN in chondrocytes within OA lesions of articular cartilage (PubMed:17827158)
Applications
WB
Field of Research
Cancer, Cardiovascular, Developmental Biology, Metabolism, Signal Transduction, Stem Cells, Cytokines
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/mL.
Function
Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
44341 Da
Applications Notes
WB: 1:2000
Subcellular Location
[Latency-associated peptide]: Secreted, extracellular space, extracellular matrix
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-TGFB1 Antibody?

The catalog number for Anti-TGFB1 Antibody is A00019-1-400ul.

What sizes are available for Anti-TGFB1 Antibody?

Anti-TGFB1 Antibody is available in the following size(s): 400 µL.

Is Anti-TGFB1 Antibody in stock?

Anti-TGFB1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-TGFB1 Antibody?

The safety data sheet for Anti-TGFB1 Antibody is available here: https://www.bosterbio.com/msds?sku=A00019-1.

What is Anti-TGFB1 Antibody used for?

Boster Bio Anti-TGFB1 Antibody (Catalog # A00019-1) . Tested in WB application (s) . This antibody reacts with Human, Rat.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

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