Anti-CD152 CTLA4 Antibody

About this product

Boster Bio Anti-CD152 CTLA4 Antibody catalog # A00020. Tested in IHC, IF, ELISA applications. This antibody reacts with Human, Mouse.

Specifications

Catalog number

A00020

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Cytotoxic T-lymphocyte protein 4; Cytotoxic T-lymphocyte-associated antigen 4; CTLA-4; CD152; CTLA4; CD152

Gene Name

CTLA4

UniProt

P16410

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthetic peptide from human protein at AA range: 41-90

Clonality

Polyclonal

Tissue Specificity

Widely expressed with highest levels in lymphoid tissues. Detected in activated T-cells where expression levels are 30- to 50-fold less than CD28, the stimulatory coreceptor, on the cell surface following activation. .

Applications

IHC, IF, ELISA

Purification

Immunogen affinity purified

Concentration

1 mg/mL

Form

Liquid

Function

Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

24656 MW

Gene Name Synonym

Cytotoxic T-lymphocyte protein 4

Subcellular Location

Cell membrane ; Single-pass type I membrane protein . Exists primarily an intracellular antigen whose surface expression is tightly regulated by restricted trafficking to the cell surface and rapid internalisation; .

Isotype

IgG

Contents

PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.