Anti-C-C motif chemokine 2 CCL2 Antibody

About this product

Boster Bio Anti-C-C motif chemokine 2 CCL2 Antibody (Catalog # A00056) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

A00056

Size / count

0.1 mg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CCL2, also known as monocyte chemotactic protein 1 (MCP1), belongs to the intercrine beta (chemokine CC) family. It is produced by a variety of cell types and is a potent chemoattractant for monocytes, memory T lymphocytes, and natural killer (NK) cells. It is upregulated during infection and inflammation. CCL2 is a potent basophil activator but does not affect eosinophils, whereas the related protein MCP2 stimulates both eosinophils and basophils. MCP3 has been shown to have the broadest range of influence. CCL2 has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis.

Synonyms

HC11, MCAF, MCP1, MCP-1, SCYA2, GDCF-2, SMC-CF, HSMCR30, C-C motif chemokine 2, HC11

Gene Name

CCL2

UniProt

P13500

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Rabbit polyclonal CCL2 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human CCL2. The immunogen is located within the last 50 amino acids of CCL2.

Clonality

Polyclonal

Tissue Specificity

Expressed in the seminal plasma, endometrial fluid and follicular fluid (at protein level) .

Applications

ELISA, WB, IHC-P, IF

Field of Research

Immunology

Purification

CCL2 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.

Storage Conditions

CCL2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Observed Molecular Weight

11025 MW

Gene Name Synonym

Chemokine (C-C motif) ligand 2

Subcellular Location

Secreted

Prediction Reactivity

Pig, Horse, Bovine, Rabbit, Guinea Pig

Protein Name

Chemokine (C-C motif) ligand 2

Isotype

IgG

Contents

CCL2 Antibody is supplied in PBS containing 0.02% sodium azide.