Anti-Smad2/3 (S2) SMAD3 Antibody — image 1 of 2

Product details

Anti-Smad2/3 (S2) SMAD3 Antibody

Catalog number A00059S2

Price for A00059S2

Size / count 100 µL

About this product

Boster Bio Anti-Smad2/3 (S2) SMAD3 Antibody catalog # A00059S2. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: A00059S2
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Mothers against decapentaplegic homolog 3; MAD homolog 3; Mad3; Mothers against DPP homolog 3; hMAD-3; JV15-2; SMAD family member 3; SMAD 3; Smad3; hSMAD3; SMAD3; MADH3
Gene Name: SMAD3
UniProt: P84022/Q15796
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to the N-terminal of Human Smad2.
Clonality: Polyclonal
Applications: WB, IHC
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration: 1 mg/mL
Form: Liquid
Function: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription. Also can form a SMAD3/SMAD4/JUN/FOS complex at the AP-1/SMAD site to regulate TGF-beta-mediated transcription. Has an inhibitory effect on wound healing probably by modulating both growth and migration of primary keratinocytes and by altering the TGF- mediated chemotaxis of monocytes. This effect on wound healing appears to be hormone-sensitive. Regulator of chondrogenesis and osteogenesis and inhibits early healing of bone fractures. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight: 48081 MW
Gene Name Synonym: Mothers against decapentaplegic homolog 3
Subcellular Location: Cytoplasm
Protein Name: Mothers against decapentaplegic homolog 3
Contents: Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-Smad2/3 (S2) SMAD3 Antibody?

The catalog number for Anti-Smad2/3 (S2) SMAD3 Antibody is A00059S2.

What sizes are available for Anti-Smad2/3 (S2) SMAD3 Antibody?

Anti-Smad2/3 (S2) SMAD3 Antibody is available in the following size(s): 100 µL.

Is Anti-Smad2/3 (S2) SMAD3 Antibody in stock?

Anti-Smad2/3 (S2) SMAD3 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-Smad2/3 (S2) SMAD3 Antibody?

The safety data sheet for Anti-Smad2/3 (S2) SMAD3 Antibody is available here: https://www.bosterbio.com/msds?sku=A00059S2.

What is Anti-Smad2/3 (S2) SMAD3 Antibody used for?

Boster Bio Anti-Smad2/3 (S2) SMAD3 Antibody catalog # A00059S2. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.