Anti-CD28 Antibody

About this product

Boster Bio Anti-CD28 Antibody (Catalog # A00065) . Tested in ELISA, WB, IHC, IF applications. This antibody reacts with Human.

Specifications

Catalog number

A00065

Size / count

0.1 mg

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

CD28 Molecule, CD28 Antigen, Tp44, T-Cell-Specific Surface Glycoprotein CD28, T-Cell-Specific Surface Glycoprotein, CD28 Antigen (Tp44)

Gene Name

CD28

UniProt

P10747

Host

Rabbit

Reactivity

Human

Immunogen

CD28 antibody was raised against a peptide corresponding to 18 amino acids near the carboxy terminus of human CD28. The immunogen is located within the last 50 amino acids of CD28.

Clonality

Polyclonal

Tissue Specificity

Expressed in T-cells and plasma cells, but not in less mature B-cells.

Applications

ELISA, WB, IHC, IF

Field of Research

Immunology

Purification

CD28 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation (PubMed:8617933) . Isoform 3 enhances CD40L-mediated activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells (PubMed:15067037) .

Storage Conditions

CD28 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Observed Molecular Weight

25066 MW

Gene Name Synonym

CD28 molecule

Subcellular Location

Membrane; Single-pass type I membrane protein.

Prediction Reactivity

Rabbit, Bovine, Cat, Rat, Mouse

Protein Name

CD28 molecule

Isotype

IgG

Contents

CD28 Antibody is supplied in PBS containing 0.02% sodium azide.