Anti-VHL Antibody (C-term)

Catalog number A00079-2-400ul

Price for A00079-2-400ul

Size / count 400 µL

About this product

Boster Bio Anti-VHL Antibody (C-term) (Catalog # A00079-2) . Tested in IHC-P, Flow Cytometry, WB application (s) . This antibody reacts with Human.

Specifications

Catalog number: A00079-2-400ul
Size / count: 400 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of VHL gene is the basis of familial inheritance of VHL syndrome. The protein is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein.
Synonyms: Von Hippel-Lindau disease tumor suppressor, Protein G7, pVHL, VHL
Gene Name: VHL
UniProt: P40337
Host: Rabbit
Reactivity: Human
Immunogen: This VHL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-210 amino acids from the C-terminal region of human VHL.
Clonality: Polyclonal
Tissue Specificity: Expressed in the adult and fetal brain and kidney.
Applications: IHC-P, Flow Cytometry, WB
Field of Research: Cancer, Cell Biology, Metabolism
Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function: 109441131798112419584355109441131798112410944113179811241958435534290272
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 24153 Da
Subcellular Location: [Isoform 1]: Cytoplasm. Cell membrane; Peripheral membrane protein. Endoplasmic reticulum. Nucleus. Note=Found predominantly in the cytoplasm and with less amounts nuclear or membrane-associated (PubMed:9751722) Colocalizes with ADRB2 at the cell membrane (PubMed:19584355)
Isotype: Rabbit IgG
Contents: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-VHL Antibody (C-term)?

The catalog number for Anti-VHL Antibody (C-term) is A00079-2-400ul.

What sizes are available for Anti-VHL Antibody (C-term)?

Anti-VHL Antibody (C-term) is available in the following size(s): 400 µL.

Is Anti-VHL Antibody (C-term) in stock?

Anti-VHL Antibody (C-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-VHL Antibody (C-term)?

The safety data sheet for Anti-VHL Antibody (C-term) is available here: https://www.bosterbio.com/msds?sku=A00079-2.

What is Anti-VHL Antibody (C-term) used for?

Boster Bio Anti-VHL Antibody (C-term) (Catalog # A00079-2) . Tested in IHC-P, Flow Cytometry, WB application (s) . This antibody reacts with Human.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.