Anti-CBS Antibody (Center)

About this product

Boster Bio Anti-CBS Antibody (Center) (Catalog # A00130-2) . Tested in WB, IHC-P-Leica, Flow Cytometry, IF application (s) . This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

A00130-2-80ul

Size / count

80 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

CBS acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. This protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria.

Synonyms

Cystathionine beta-synthase, Beta-thionase, Serine sulfhydrase, CBS

Gene Name

CBS

UniProt

P35520

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

This CBS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 301-330 amino acids from the Central region of human CBS.

Clonality

Polyclonal

Tissue Specificity

In the adult strongly expressed in liver and pancreas, some expression in heart and brain, weak expression in lung and kidney. In the fetus, expressed in brain, liver and kidney

Applications

WB, IHC-P-Leica, Flow Cytometry, IF

Field of Research

Cancer, Metabolism, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

239817742050632523974653

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

60587 Da

Subcellular Location

Cytoplasm. Nucleus

Prediction Reactivity

Monkey

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.