Anti-p21 (phospho-T145) CDKN1A Antibody

Catalog number A00145T145

Price for A00145T145

Size / count 100 µL

About this product

Boster Bio Anti-p21 (phospho-T145) CDKN1A Antibody catalog # A00145T145. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: A00145T145
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6; p21; CDKN1A; CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1
Gene Name: CDKN1A
UniProt: P38936
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic phosphopeptide derived from human p21 around the phosphorylation site of Threonine 145.
Clonality: Polyclonal
Tissue Specificity: Expressed in all adult tissues, with 5-fold lower levels observed in the brain.
Applications: IHC
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration: 1 mg/mL
Form: Liquid
Function: May be involved in p53/TP53 mediated inhibition of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex. Inhibits DNA synthesis by DNA polymerase delta by competing with POLD3 for PCNA binding (PubMed:11595739) .
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight: 18119 MW
Applications Notes: IHC: 1:50-1:200
Gene Name Synonym: Cyclin-dependent kinase inhibitor 1
Subcellular Location: Cytoplasm. Nucleus.
Protein Name: Cyclin-dependent kinase inhibitor 1
Contents: Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-p21 (phospho-T145) CDKN1A Antibody?

The catalog number for Anti-p21 (phospho-T145) CDKN1A Antibody is A00145T145.

What sizes are available for Anti-p21 (phospho-T145) CDKN1A Antibody?

Anti-p21 (phospho-T145) CDKN1A Antibody is available in the following size(s): 100 µL.

Is Anti-p21 (phospho-T145) CDKN1A Antibody in stock?

Anti-p21 (phospho-T145) CDKN1A Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-p21 (phospho-T145) CDKN1A Antibody?

The safety data sheet for Anti-p21 (phospho-T145) CDKN1A Antibody is available here: https://www.bosterbio.com/msds?sku=A00145T145.

What is Anti-p21 (phospho-T145) CDKN1A Antibody used for?

Boster Bio Anti-p21 (phospho-T145) CDKN1A Antibody catalog # A00145T145. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.