Anti-CD19 Antibody (N-term)

About this product

Boster Bio Anti-CD19 Antibody (N-term) (Catalog # A00154) . Tested in WB, IHC-P, Flow Cytometry, IF application (s) . This antibody reacts with Human.

Specifications

Catalog number

A00154-80ul

Size / count

80 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. CD19 is a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.

Synonyms

B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, Differentiation antigen CD19, T-cell surface antigen Leu-12, CD19, CD19

Gene Name

CD19

UniProt

P15391

Host

Rabbit

Reactivity

Human

Immunogen

This CD19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-172 amino acids from the N-terminal region of human CD19.

Clonality

Polyclonal

Tissue Specificity

Detected on marginal zone and germinal center B cells in lymph nodes (PubMed:2463100) . Detected on blood B cells (at protein level) (PubMed:2463100, PubMed:16672701)

Applications

WB, IHC-P, Flow Cytometry, IF

Field of Research

Cancer, Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

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Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

61128 Da

Subcellular Location

Cell membrane; Single-pass type I membrane protein. Membrane raft {ECO:0000250|UniProtKB:P25918}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P25918}

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.