Anti-Histone H2A.X/H2AFX Antibody

About this product

Boster Bio Anti-Histone H2A.X/H2AFX Antibody catalog # A00241-4. Tested in WB, IHC, ICC, IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat, Monkey.

Specifications

Catalog number

A00241-4

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

H2A histone family member X (usually abbreviated as H2AX) is a type of histone protein from the H2A family encoded by the H2AFX gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

Gene Name

H2AX

UniProt

P16104

Host

Rabbit

Reactivity

Human, Monkey, Mouse, Rat

Immunogen

E.coli-derived human Histone H2A.X/H2AFX recombinant protein (Position: S2-S140) .

Clonality

Polyclonal

Applications

WB, IHC, ICC, IF, Flow Cytometry, ELISA

Purification

Immunogen affinity purified.

Concentration

500 μg/mL

Form

Liquid

Storage Conditions

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

Applications Notes

6

Contents

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.