Anti-SREBF1 Antibody

About this product

Boster Bio Anti-SREBF1 Antibody catalog # A00282-2. Tested in WB, IHC, ICC, IF, IP, ELISA applications. This antibody reacts with Human, Rat.

Specifications

Catalog number

A00282-2

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

This gene encodes a basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a motif that is found in the promoter of the low density lipoprotein receptor gene and other genes involved in sterol biosynthesis. The encoded protein is synthesized as a precursor that is initially attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription. This cleaveage is inhibited by sterols. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative promoter usage and splicing result in multiple transcript variants, including SREBP-1a and SREBP-1c, which correspond to RefSeq transcript variants 2 and 3, respectively.

Gene Name

SREBF1

UniProt

P36956

Host

Rabbit

Reactivity

Human, Rat

Immunogen

E.coli-derived human SREBF1 recombinant protein (Position: E3-A330) .

Clonality

Polyclonal

Applications

WB, IHC, ICC, IF, IP, ELISA

Purification

Immunogen affinity purified.

Concentration

500 μg/mL

Form

Liquid

Storage Conditions

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

Contents

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.