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Product details

Anti-IFNAR1 Antibody (Center)

Catalog number A00306-400ul

Price for A00306-400ul

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Size / count 400 µL

About this product

Boster Bio Anti-IFNAR1 Antibody (Center) (Catalog # A00306) . Tested in WB, Flow Cytometry, IHC-P-Leica application (s) . This antibody reacts with Human.

Specifications

Catalog number
A00306-400ul
Size / count
400 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
IFNAR1 is the receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha-and beta-subunits themselves.
Synonyms
Interferon alpha/beta receptor 1, IFN-R-1, IFN-alpha/beta receptor 1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, CRF2-1, Type I interferon receptor 1, IFNAR1, IFNAR
Gene Name
IFNAR1
UniProt
P17181
Host
Rabbit
Reactivity
Human
Immunogen
This IFNAR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-188 amino acids of human IFNAR1.
Clonality
Polyclonal
Tissue Specificity
IFN receptors are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN- alpha resistant myeloma cell line U266R.
Applications
WB, Flow Cytometry, IHC-P-Leica
Field of Research
Cancer, Immunology, Signal Transduction, TLR Signaling, Inflammation, Lysosome
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
215346178134271004974414532120153377702407598521854986312702473325264435442418766557410049744218549867813427766557421854986329729957813427752615476655742185498632972995781342776655749121453195610672185498632972995
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
63525 Da
Subcellular Location
[Isoform 1]: Cell membrane; Single-pass type I membrane protein. Late endosome. Lysosome. Note=Interferon binding triggers internalization of the receptor from the cell membrane into endosomes and then into lysosomes.
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-IFNAR1 Antibody (Center)?

The catalog number for Anti-IFNAR1 Antibody (Center) is A00306-400ul.

What sizes are available for Anti-IFNAR1 Antibody (Center)?

Anti-IFNAR1 Antibody (Center) is available in the following size(s): 400 µL.

Is Anti-IFNAR1 Antibody (Center) in stock?

Anti-IFNAR1 Antibody (Center) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-IFNAR1 Antibody (Center)?

The safety data sheet for Anti-IFNAR1 Antibody (Center) is available here: https://www.bosterbio.com/msds?sku=A00306.

What is Anti-IFNAR1 Antibody (Center) used for?

Boster Bio Anti-IFNAR1 Antibody (Center) (Catalog # A00306) . Tested in WB, Flow Cytometry, IHC-P-Leica application (s) . This antibody reacts with Human.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

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