Anti-MIP-1 alpha CCL3 Antibody

About this product

Boster Bio Anti-MIP-1 alpha CCL3 Antibody (Catalog # A00405) . Tested in WB applications. This antibody reacts with Mouse.

Specifications

Catalog number

A00405

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Mouse MIP-1α, or Ccl3, of the intercrine beta (chemokine CC family) is a secreted cytokine with inflammatory, pyrogenic and chemokinetic properties. It is expressed in lung, spleen, and pancreas, and has a potent chemotactic activity for eosinophils. Ccl3 binding to a high-affinity receptor activates calcium release in neutrophils.

Synonyms

MIP-1α, MIP-1 alpha, Mouse Macrophage Inflammatory Protein-1-alpha, Ccl3 cytokine, C-C motif chemokine 3, Small-inducible cytokine A3, Macrophage inflammatory protein 1-α, MIP-1-alpha, TY-5, SIS-alpha, Heparin-binding chemotaxis protein, L2G25B, Scya3 protein

Gene Name

CCL3

UniProt

P10855

Host

Rabbit

Reactivity

Mouse

Immunogen

This IgG fraction antibody was prepared from rabbit antiserum after repeated immunizations with recombinant truncated mouse MIP-1α protein produced in E.coli.

Clonality

Polyclonal

Applications

ELISA, WB

Field of Research

Antiviral Signaling, Chemokines, Immune System Diseases, Immunology, Innate Immunity, Macrophage/Inflammation

Purification

This product is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above. This antibody is specific for mouse MIP-1α protein. Cross-reactivity with MIP-1α from other sources has not been determined.

Concentration

1.0 mg/mL by UV absorbance at 280 nm

Form

Lyophilized

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 100 μL

Storage Conditions

Store vial at 4°C prior to restoration. For extended storage aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is six (6) months from date of opening. (Ship at ambient temperature.)

Observed Molecular Weight

10085 MW

Gene Name Synonym

C-C motif chemokine

Subcellular Location

Secreted.

Isotype

IgG

Contents

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2