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Product details

Anti-EPOR Antibody (C-term)

Catalog number A00427-3-400ul

Price for A00427-3-400ul

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Size / count 400 µL

About this product

Boster Bio Anti-EPOR Antibody (C-term) (Catalog # A00427-3) . Tested in WB, Flow Cytometry application (s) . This antibody reacts with Human.

Specifications

Catalog number
A00427-3-400ul
Size / count
400 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Receptor for erythropoietin. Mediates erythropoietin- induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.
Synonyms
Erythropoietin receptor, EPO-R, EPOR
Gene Name
EPOR
UniProt
P19235
Host
Rabbit
Reactivity
Human
Immunogen
This EPOR antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 470-504 amino acids from the C-terminal region of human EPOR.
Clonality
Polyclonal
Tissue Specificity
Erythroid cells and erythroid progenitor cells. Isoform EPOR-F is the most abundant form in EPO-dependent erythroleukemia cells and in late-stage erythroid progenitors. Isoform EPOR-S and isoform EPOR-T are the predominant forms in bone marrow Isoform EPOR-T is the most abundant from in early-stage erythroid progenitor cells
Applications
WB, Flow Cytometry
Field of Research
Cardiovascular, Immunology, Signal Transduction, Stem Cells
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
55065 Da
Subcellular Location
Cell membrane; Single-pass type I membrane protein
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-EPOR Antibody (C-term)?

The catalog number for Anti-EPOR Antibody (C-term) is A00427-3-400ul.

What sizes are available for Anti-EPOR Antibody (C-term)?

Anti-EPOR Antibody (C-term) is available in the following size(s): 400 µL.

Is Anti-EPOR Antibody (C-term) in stock?

Anti-EPOR Antibody (C-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-EPOR Antibody (C-term)?

The safety data sheet for Anti-EPOR Antibody (C-term) is available here: https://www.bosterbio.com/msds?sku=A00427-3.

What is Anti-EPOR Antibody (C-term) used for?

Boster Bio Anti-EPOR Antibody (C-term) (Catalog # A00427-3) . Tested in WB, Flow Cytometry application (s) . This antibody reacts with Human.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

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