Anti-AIM2 (A78) Antibody

Catalog number A00443

Price for A00443

Size / count 100 µL

About this product

Boster Bio Anti-AIM2 (A78) Antibody catalog # A00443. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: A00443
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Interferon-inducible protein AIM2; Absent in melanoma 2; AIM2
Gene Name: AIM2
UniProt: O14862
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to amino acids 51-100 of Human AIM2.
Clonality: Polyclonal
Tissue Specificity: Expressed in spleen, small intestine, peripheral blood leukocytes, and testis.
Applications: IHC
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration: 1 mg/mL
Form: Liquid
Function: Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8 (By similarity) . Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity.
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight: 38954 MW
Applications Notes: IHC: 1:50-1:200
Gene Name Synonym: Interferon-inducible protein AIM2
Subcellular Location: Nucleus. Cytoplasm. Activated inflammasomes can aggregate in the cytosol as speck-like particles.
Protein Name: Interferon-inducible protein AIM2
Contents: Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-AIM2 (A78) Antibody?

The catalog number for Anti-AIM2 (A78) Antibody is A00443.

What sizes are available for Anti-AIM2 (A78) Antibody?

Anti-AIM2 (A78) Antibody is available in the following size(s): 100 µL.

Is Anti-AIM2 (A78) Antibody in stock?

Anti-AIM2 (A78) Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-AIM2 (A78) Antibody?

The safety data sheet for Anti-AIM2 (A78) Antibody is available here: https://www.bosterbio.com/msds?sku=A00443.

What is Anti-AIM2 (A78) Antibody used for?

Boster Bio Anti-AIM2 (A78) Antibody catalog # A00443. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.