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Product details

Anti-NPM1 Antibody (N-term)

Catalog number A00450-80ul

Price for A00450-80ul

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Size / count 80 µL

About this product

Boster Bio Anti-NPM1 Antibody (N-term) (Catalog # A00450) . Tested in WB, IF, IHC-P, Flow Cytometry application (s) . This antibody reacts with Human.

Specifications

Catalog number
A00450-80ul
Size / count
80 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
NPM1 is a ubiquitously expressed nucleolar protein that shuttles between the nucleus and cytoplasm. It is implicated in multiple functions, including ribosomal protein assembly and transport, control of centrosome duplication, and regulation of the tumor suppressor ARF. NPM1 mutations that relocalize NPM1 from the nucleus into the cytoplasm are associated with development of acute myeloid leukemia.
Synonyms
Nucleophosmin, NPM, Nucleolar phosphoprotein B23, Nucleolar protein NO38, Numatrin, NPM1, NPM
Gene Name
NPM1
UniProt
P06748
Host
Rabbit
Reactivity
Human
Immunogen
This NPM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-33 amino acids from the N-terminal region of human NPM1.
Clonality
Polyclonal
Applications
WB, IF, IHC-P, Flow Cytometry
Field of Research
Viral process, Host-Virus Interaction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function
2252848625956029
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
32575 Da
Subcellular Location
Nucleus, nucleolus. Nucleus, nucleoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Note=Generally nucleolar, but is translocated to the nucleoplasm in case of serum starvation or treatment with anticancer drugs. Has been found in the cytoplasm in patients with primary acute myelogenous leukemia (AML), but not with secondary AML. Can shuttle between cytoplasm and nucleus. Co- localizes with the methylated form of RPS10 in the granular component (GC) region of the nucleolus. Colocalized with nucleolin and APEX1 in nucleoli. Isoform 1 of NEK2 is required for its localization to the centrosome during mitosis
Prediction Reactivity
Mouse, Rat
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-NPM1 Antibody (N-term)?

The catalog number for Anti-NPM1 Antibody (N-term) is A00450-80ul.

What sizes are available for Anti-NPM1 Antibody (N-term)?

Anti-NPM1 Antibody (N-term) is available in the following size(s): 80 µL.

Is Anti-NPM1 Antibody (N-term) in stock?

Anti-NPM1 Antibody (N-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-NPM1 Antibody (N-term)?

The safety data sheet for Anti-NPM1 Antibody (N-term) is available here: https://www.bosterbio.com/msds?sku=A00450.

What is Anti-NPM1 Antibody (N-term) used for?

Boster Bio Anti-NPM1 Antibody (N-term) (Catalog # A00450) . Tested in WB, IF, IHC-P, Flow Cytometry application (s) . This antibody reacts with Human.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

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