Anti-NPM1 Antibody (N-term) — image 1 of 2

Product details

Anti-NPM1 Antibody (N-term)

Catalog number A00450-400ul

Price for A00450-400ul

Size / count 400 µL

About this product

Boster Bio Anti-NPM1 Antibody (N-term) (Catalog # A00450) . Tested in WB, IF, IHC-P, Flow Cytometry application (s) . This antibody reacts with Human.

Specifications

Catalog number: A00450-400ul
Size / count: 400 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: NPM1 is a ubiquitously expressed nucleolar protein that shuttles between the nucleus and cytoplasm. It is implicated in multiple functions, including ribosomal protein assembly and transport, control of centrosome duplication, and regulation of the tumor suppressor ARF. NPM1 mutations that relocalize NPM1 from the nucleus into the cytoplasm are associated with development of acute myeloid leukemia.
Synonyms: Nucleophosmin, NPM, Nucleolar phosphoprotein B23, Nucleolar protein NO38, Numatrin, NPM1, NPM
Gene Name: NPM1
UniProt: P06748
Host: Rabbit
Reactivity: Human
Immunogen: This NPM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-33 amino acids from the N-terminal region of human NPM1.
Clonality: Polyclonal
Applications: WB, IF, IHC-P, Flow Cytometry
Field of Research: Viral process, Host-Virus Interaction
Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function: 2252848625956029
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 32575 Da
Subcellular Location: Nucleus, nucleolus. Nucleus, nucleoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Note=Generally nucleolar, but is translocated to the nucleoplasm in case of serum starvation or treatment with anticancer drugs. Has been found in the cytoplasm in patients with primary acute myelogenous leukemia (AML), but not with secondary AML. Can shuttle between cytoplasm and nucleus. Co- localizes with the methylated form of RPS10 in the granular component (GC) region of the nucleolus. Colocalized with nucleolin and APEX1 in nucleoli. Isoform 1 of NEK2 is required for its localization to the centrosome during mitosis
Prediction Reactivity: Mouse, Rat
Isotype: Rabbit IgG
Contents: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-NPM1 Antibody (N-term)?

The catalog number for Anti-NPM1 Antibody (N-term) is A00450-400ul.

What sizes are available for Anti-NPM1 Antibody (N-term)?

Anti-NPM1 Antibody (N-term) is available in the following size(s): 400 µL.

Is Anti-NPM1 Antibody (N-term) in stock?

Anti-NPM1 Antibody (N-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-NPM1 Antibody (N-term)?

The safety data sheet for Anti-NPM1 Antibody (N-term) is available here: https://www.bosterbio.com/msds?sku=A00450.

What is Anti-NPM1 Antibody (N-term) used for?

Boster Bio Anti-NPM1 Antibody (N-term) (Catalog # A00450) . Tested in WB, IF, IHC-P, Flow Cytometry application (s) . This antibody reacts with Human.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.