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Product details

Anti-CAD Antibody (Center)

Catalog number A00463-3-400ul

Price for A00463-3-400ul

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Size / count 400 µL

About this product

Boster Bio Anti-CAD Antibody (Center) (Catalog # A00463-3) . Tested in WB, IHC-P, Flow Cytometry application (s) . This antibody reacts with Human.

Specifications

Catalog number
A00463-3-400ul
Size / count
400 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.
Synonyms
CAD protein, Glutamine-dependent carbamoyl-phosphate synthase, Aspartate carbamoyltransferase, Dihydroorotase, CAD
Gene Name
CAD
UniProt
P27708
Host
Rabbit
Reactivity
Human
Immunogen
This CAD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 780-809 amino acids from the Central region of human CAD.
Clonality
Polyclonal
Applications
WB, IHC-P, Flow Cytometry
Field of Research
Cell Biology, Metabolism
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
This protein is a 'fusion' protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) .
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
242984 Da
Subcellular Location
Cytoplasm. Nucleus. Note=Cytosolic and unphosphorylated in resting cells, translocates to the nucleus in response to EGF stimulation, nuclear import promotes optimal cell growth
Prediction Reactivity
Mouse
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-CAD Antibody (Center)?

The catalog number for Anti-CAD Antibody (Center) is A00463-3-400ul.

What sizes are available for Anti-CAD Antibody (Center)?

Anti-CAD Antibody (Center) is available in the following size(s): 400 µL.

Is Anti-CAD Antibody (Center) in stock?

Anti-CAD Antibody (Center) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-CAD Antibody (Center)?

The safety data sheet for Anti-CAD Antibody (Center) is available here: https://www.bosterbio.com/msds?sku=A00463-3.

What is Anti-CAD Antibody (Center) used for?

Boster Bio Anti-CAD Antibody (Center) (Catalog # A00463-3) . Tested in WB, IHC-P, Flow Cytometry application (s) . This antibody reacts with Human.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

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