Anti-MERTK Antibody

About this product

Boster Bio Anti-MERTK Antibody (Catalog # A00489-3) . Tested in WB, IF, Flow Cytometry, IHC-P application (s) . This antibody reacts with Human.

Specifications

Catalog number

A00489-3-400ul

Size / count

400 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

MERTK is a member of the MER/AXL/TYRO3 receptor kinase family and a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in MERTK gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP) .

Synonyms

Tyrosine-protein kinase Mer, Proto-oncogene c-Mer, Receptor tyrosine kinase MerTK, MERTK, MER

Gene Name

MERTK

UniProt

Q12866

Host

Rabbit

Reactivity

Human

Immunogen

This MERTK antibody is generated from rabbits immunized with a his tag recombinant protein of human MERTK.

Clonality

Polyclonal

Tissue Specificity

Not expressed in normal B- and T-lymphocytes but is expressed in numerous neoplastic B- and T-cell lines. Highly expressed in testis, ovary, prostate, lung, and kidney, with lower expression in spleen, small intestine, colon, and liver

Applications

WB, IF, Flow Cytometry, IHC-P

Field of Research

Cell Biology, Immunology, Neuroscience, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Function

32640697

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

110249 Da

Subcellular Location

Cell membrane; Single-pass type I membrane protein

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.