Anti-Protein Wnt-5a Wnt5a Antibody — image 1 of 2

Product details

Anti-Protein Wnt-5a Wnt5a Antibody

Catalog number A00549

Price for A00549

Size / count 100 µL

About this product

Boster Bio Anti-Protein Wnt-5a Wnt5a Antibody catalog # A00549. Tested in WB, ICC, IHC, Flow Cytometry applications. This antibody reacts with Human.

Specifications

Catalog number: A00549
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Protein Wnt-5a; WNT5A
Gene Name: WNT5A
UniProt: P41221
Host: Rabbit
Reactivity: Human
Immunogen: Recombinant protein
Clonality: Polyclonal
Tissue Specificity: Expression is increased in differentiated thyroid carcinomas compared to normal thyroid tissue and anaplastic thyroid tumors where expression is low or undetectable. Expression is found in thyrocytes but not in stromal cells (at protein level) (PubMed:15735754) . Detected in neonate heart and lung (PubMed:8288227) .
Applications: WB, ICC, IHC, Flow Cytometry
Purification: ProA affinity purified
Concentration: 1 mg/mL
Form: Liquid
Function: Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression (By similarity) . Suppression of the canonical pathway allows chondrogenesis to occur and inhibits tumor formation. Stimulates cell migration. Decreases proliferation, migration, invasiveness and clonogenicity of carcinoma cells and may act as a tumor suppressor (PubMed:15735754) . Mediates motility of melanoma cells (PubMed:17426020) . Required during embryogenesis for extension of the primary anterior-posterior axis and for outgrowth of limbs and the genital tubercle. Inhibits type II collagen expression in chondrocytes (By similarity) .
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight: 42339 MW
Gene Name Synonym: Protein Wnt-5a
Subcellular Location: Secreted, extracellular space, extracellular matrix . Secreted
Protein Name: Protein Wnt-5a
Contents: Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-Protein Wnt-5a Wnt5a Antibody?

The catalog number for Anti-Protein Wnt-5a Wnt5a Antibody is A00549.

What sizes are available for Anti-Protein Wnt-5a Wnt5a Antibody?

Anti-Protein Wnt-5a Wnt5a Antibody is available in the following size(s): 100 µL.

Is Anti-Protein Wnt-5a Wnt5a Antibody in stock?

Anti-Protein Wnt-5a Wnt5a Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-Protein Wnt-5a Wnt5a Antibody?

The safety data sheet for Anti-Protein Wnt-5a Wnt5a Antibody is available here: https://www.bosterbio.com/msds?sku=A00549.

What is Anti-Protein Wnt-5a Wnt5a Antibody used for?

Boster Bio Anti-Protein Wnt-5a Wnt5a Antibody catalog # A00549. Tested in WB, ICC, IHC, Flow Cytometry applications. This antibody reacts with Human.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.