Anti-SRF (phospho-S103) Antibody

About this product

Boster Bio Anti-SRF (phospho-S103) Antibody catalog # A00557S103. Tested in WB, IHC applications. This antibody reacts with Human.

Specifications

Catalog number

A00557S103

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Serum response factor; SRF; SRF

Gene Name

SRF

UniProt

P11831

Host

Rabbit

Reactivity

Human

Immunogen

Synthetic phosphopeptide derived from human SRF around the phosphorylation site of Serine 103.

Clonality

Polyclonal

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS) . Together with MRTFA transcription coactivator, controls expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration. The SRF-MRTFA complex activity responds to Rho GTPase-induced changes in cellular globular actin (G-actin) concentration, thereby coupling cytoskeletal gene expression to cytoskeletal dynamics. Required for cardiac differentiation and maturation.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

51593 MW

Gene Name Synonym

Serum response factor

Subcellular Location

Nucleus

Protein Name

Serum response factor

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2