Anti-Fibronectin 1 FN1 Antibody

About this product

Boster Bio Anti-Fibronectin 1 FN1 Antibody catalog # A00564. Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

A00564

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Fibronectin; FN; Cold-insoluble globulin; CIG; Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3; FN1; FN

Gene Name

FN1

UniProt

P02751

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human FN1

Clonality

Polyclonal

Tissue Specificity

Plasma FN (soluble dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. Ugl-Y1, Ugl-Y2 and Ugl-Y3 are found in urine.

Applications

WB, IHC, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

262625 MW

Gene Name Synonym

Fibronectin

Subcellular Location

Secreted, extracellular space, extracellular matrix.

Protein Name

Fibronectin

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2