Anti-FGA Antibody (N-term)

Catalog number A00816-80ul

Price for A00816-80ul

Size / count 80 µL

About this product

Boster Bio Anti-FGA Antibody (N-term) (Catalog # A00816) . Tested in WB, IF, IHC-P application (s) . This antibody reacts with Human.

Specifications

Catalog number: A00816-80ul
Size / count: 80 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: FGA is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types.
Synonyms: Fibrinogen alpha chain, Fibrinopeptide A, Fibrinogen alpha chain, FGA
Gene Name: FGA
UniProt: P02671
Host: Rabbit
Reactivity: Human
Immunogen: This FGA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-144 amino acids from the N-terminal region of human FGA.
Clonality: Polyclonal
Tissue Specificity: Detected in blood plasma (at protein level) .
Applications: WB, IF, IHC-P
Field of Research: Cardiovascular, Metabolism, Immunology, Innate Immunity
Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function: Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re- epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways.
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 94973 Da
Subcellular Location: Secreted
Isotype: Rabbit IgG
Contents: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-FGA Antibody (N-term)?

The catalog number for Anti-FGA Antibody (N-term) is A00816-80ul.

What sizes are available for Anti-FGA Antibody (N-term)?

Anti-FGA Antibody (N-term) is available in the following size(s): 80 µL.

Is Anti-FGA Antibody (N-term) in stock?

Anti-FGA Antibody (N-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-FGA Antibody (N-term)?

The safety data sheet for Anti-FGA Antibody (N-term) is available here: https://www.bosterbio.com/msds?sku=A00816.

What is Anti-FGA Antibody (N-term) used for?

Boster Bio Anti-FGA Antibody (N-term) (Catalog # A00816) . Tested in WB, IF, IHC-P application (s) . This antibody reacts with Human.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.