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Product details

Anti-PLA2G4A Antibody (Center)

Catalog number A00854-1-80ul

Price for A00854-1-80ul

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Size / count 80 µL

About this product

Boster Bio Anti-PLA2G4A Antibody (Center) (Catalog # A00854-1) . Tested in WB, Flow Cytometry, IF, IHC-P application (s) . This antibody reacts with Human.

Specifications

Catalog number
A00854-1-80ul
Size / count
80 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
PLA2G4A is a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca (2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles.
Synonyms
Cytosolic phospholipase A2, cPLA2, Phospholipase A2 group IVA, Phospholipase A2, Phosphatidylcholine 2-acylhydrolase, Lysophospholipase, PLA2G4A, CPLA2, PLA2G4
Gene Name
PLA2G4A
UniProt
P47712
Host
Rabbit
Reactivity
Human
Immunogen
This PLA2G4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 513-541 amino acids from the Central region of human PLA2G4A.
Clonality
Polyclonal
Tissue Specificity
Expressed in various cells and tissues such as macrophages, neutrophils, fibroblasts and lung endothelium. Expressed in platelets (at protein level) (PubMed:25102815)
Applications
WB, Flow Cytometry, IF, IHC-P
Field of Research
Cardiovascular, Immunology, Metabolism, Signal Transduction, Inflammation
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
779489186199918702602942512110358058147095601661705917472963276420671845199377948918619991942512110358058174729631845199318451993779489194251211035805817472963276420677794891126728057794891
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
85239 Da
Subcellular Location
Cytoplasm. Golgi apparatus membrane. Nucleus envelope Note=Translocates to intracellular membranes in a calcium-dependent way.
Prediction Reactivity
Chicken, Zebrafish, Horse, Mouse, Rabbit, Rat
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-PLA2G4A Antibody (Center)?

The catalog number for Anti-PLA2G4A Antibody (Center) is A00854-1-80ul.

What sizes are available for Anti-PLA2G4A Antibody (Center)?

Anti-PLA2G4A Antibody (Center) is available in the following size(s): 80 µL.

Is Anti-PLA2G4A Antibody (Center) in stock?

Anti-PLA2G4A Antibody (Center) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-PLA2G4A Antibody (Center)?

The safety data sheet for Anti-PLA2G4A Antibody (Center) is available here: https://www.bosterbio.com/msds?sku=A00854-1.

What is Anti-PLA2G4A Antibody (Center) used for?

Boster Bio Anti-PLA2G4A Antibody (Center) (Catalog # A00854-1) . Tested in WB, Flow Cytometry, IF, IHC-P application (s) . This antibody reacts with Human.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

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