Anti-PLA2G4A Antibody (Center)

Catalog number A00854-1-400ul

Price for A00854-1-400ul

Size / count 400 µL

About this product

Boster Bio Anti-PLA2G4A Antibody (Center) (Catalog # A00854-1) . Tested in WB, Flow Cytometry, IF, IHC-P application (s) . This antibody reacts with Human.

Specifications

Catalog number: A00854-1-400ul
Size / count: 400 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: PLA2G4A is a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca (2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles.
Synonyms: Cytosolic phospholipase A2, cPLA2, Phospholipase A2 group IVA, Phospholipase A2, Phosphatidylcholine 2-acylhydrolase, Lysophospholipase, PLA2G4A, CPLA2, PLA2G4
Gene Name: PLA2G4A
UniProt: P47712
Host: Rabbit
Reactivity: Human
Immunogen: This PLA2G4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 513-541 amino acids from the Central region of human PLA2G4A.
Clonality: Polyclonal
Tissue Specificity: Expressed in various cells and tissues such as macrophages, neutrophils, fibroblasts and lung endothelium. Expressed in platelets (at protein level) (PubMed:25102815)
Applications: WB, Flow Cytometry, IF, IHC-P
Field of Research: Cardiovascular, Immunology, Metabolism, Signal Transduction, Inflammation
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Function: 779489186199918702602942512110358058147095601661705917472963276420671845199377948918619991942512110358058174729631845199318451993779489194251211035805817472963276420677794891126728057794891
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 85239 Da
Subcellular Location: Cytoplasm. Golgi apparatus membrane. Nucleus envelope Note=Translocates to intracellular membranes in a calcium-dependent way.
Prediction Reactivity: Chicken, Zebrafish, Horse, Mouse, Rabbit, Rat
Isotype: Rabbit IgG
Contents: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-PLA2G4A Antibody (Center)?

The catalog number for Anti-PLA2G4A Antibody (Center) is A00854-1-400ul.

What sizes are available for Anti-PLA2G4A Antibody (Center)?

Anti-PLA2G4A Antibody (Center) is available in the following size(s): 400 µL.

Is Anti-PLA2G4A Antibody (Center) in stock?

Anti-PLA2G4A Antibody (Center) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-PLA2G4A Antibody (Center)?

The safety data sheet for Anti-PLA2G4A Antibody (Center) is available here: https://www.bosterbio.com/msds?sku=A00854-1.

What is Anti-PLA2G4A Antibody (Center) used for?

Boster Bio Anti-PLA2G4A Antibody (Center) (Catalog # A00854-1) . Tested in WB, Flow Cytometry, IF, IHC-P application (s) . This antibody reacts with Human.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.