Anti-ETS1 Antibody (N-term)

Catalog number A00931-5-400ul

Price for A00931-5-400ul

Size / count 400 µL

About this product

Boster Bio Anti-ETS1 Antibody (N-term) (Catalog # A00931-5) . Tested in WB, IF, Flow Cytometry application (s) . This antibody reacts with Human.

Specifications

Catalog number: A00931-5-400ul
Size / count: 400 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: ETS transcriptions factors, such as ETS1, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (summary by Dwyer et al., 2007 [PubMed 17986575]) .
Synonyms: Protein C-ets-1, p54, ETS1, EWSR2
Gene Name: ETS1
UniProt: P14921
Host: Rabbit
Reactivity: Human
Immunogen: This ETS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-70 amino acids from the N-terminal region of human ETS1.
Clonality: Polyclonal
Tissue Specificity: Highly expressed within lymphoid cells. Isoforms c- ETS-1A and Ets-1 p27 are both detected in all fetal tissues tested, but vary with tissue type in adult tissues. None is detected in brain or kidney.
Applications: WB, IF, Flow Cytometry
Field of Research: Cancer, Cardiovascular, Immunology
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Function: 106984921190996220378371203783711524790515592518
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 50408 Da
Subcellular Location: Nucleus. Cytoplasm Note=Delocalizes from nucleus to cytoplasm when coexpressed with isoform Ets-1 p27.
Prediction Reactivity: Mouse, Rat
Isotype: Rabbit IgG
Contents: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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