Anti-TOP2A (phospho-S1106) Antibody

About this product

Boster Bio Anti-TOP2A (phospho-S1106) Antibody catalog # A00953S1106. Tested in WB applications. This antibody reacts with Human, Rat, Mouse.

Specifications

Catalog number

A00953S1106

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

DNA topoisomerase 2-alpha;5.99.1.3; DNA topoisomerase II, alpha isozyme; TOP2A; TOP2

Gene Name

TOP2A

UniProt

P11388

Host

Rabbit

Reactivity

Human, Rat, Mouse

Immunogen

Synthetic phosphopeptide derived from human TOP2A around the phosphorylation site of Serine1106.

Clonality

Polyclonal

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

174385 MW

Applications Notes

WB: 1:500-1:1000

Gene Name Synonym

DNA topoisomerase 2-alpha

Subcellular Location

Cytoplasm

Protein Name

DNA topoisomerase 2-alpha

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2