Anti-p130 Cas (Tyr249) BCAR1 Antibody

About this product

Boster Bio Anti-p130 Cas (Tyr249) BCAR1 Antibody catalog # A00960Y249. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

A00960Y249

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Breast cancer anti-estrogen resistance protein 1; CRK-associated substrate; Cas scaffolding protein family member 1; p130cas; BCAR1; CAS, CASS1, CRKAS

Gene Name

BCAR1

UniProt

P56945

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 220-270 of Human p130 Cas.

Clonality

Polyclonal

Tissue Specificity

Widely expressed with an abundant expression in the testis. Low level of expression seen in the liver, thymus, and peripheral blood leukocytes. The protein has been detected in a B-cell line.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

93372 MW

Applications Notes

WB: 1:500-1:1000

Gene Name Synonym

Breast cancer anti-estrogen resistance protein 1

Subcellular Location

Cell junction, focal adhesion

Protein Name

Breast cancer anti-estrogen resistance protein 1

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2