Anti-Hrs (L330) HGS Antibody

Catalog number A01174

Price for A01174

Size / count 100 µL

About this product

Boster Bio Anti-Hrs (L330) HGS Antibody catalog # A01174. Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: A01174
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Hepatocyte growth factor-regulated tyrosine kinase substrate; Hrs
Gene Name: HGS
UniProt: O14964
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to amino acids 301-350 of Human Hrs.
Clonality: Polyclonal
Tissue Specificity: Ubiquitous expression in adult and fetal tissues with higher expression in testis and peripheral blood leukocytes.
Applications: WB, IHC, IF
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration: 1 mg/mL
Form: Liquid
Function: Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin-coated regions. Involved in down- regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (ESCRT-0 complex) . The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes. May contribute to the efficient recruitment of SMADs to the activin receptor complex. Involved in receptor recycling via its association with the CART complex, a multiprotein complex required for efficient transferrin receptor recycling but not for EGFR degradation.
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight: 86192 MW
Gene Name Synonym: Hepatocyte growth factor-regulated tyrosine kinase substrate
Subcellular Location: Cytoplasm
Protein Name: Hepatocyte growth factor-regulated tyrosine kinase substrate
Contents: Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-Hrs (L330) HGS Antibody?

The catalog number for Anti-Hrs (L330) HGS Antibody is A01174.

What sizes are available for Anti-Hrs (L330) HGS Antibody?

Anti-Hrs (L330) HGS Antibody is available in the following size(s): 100 µL.

Is Anti-Hrs (L330) HGS Antibody in stock?

Anti-Hrs (L330) HGS Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-Hrs (L330) HGS Antibody?

The safety data sheet for Anti-Hrs (L330) HGS Antibody is available here: https://www.bosterbio.com/msds?sku=A01174.

What is Anti-Hrs (L330) HGS Antibody used for?

Boster Bio Anti-Hrs (L330) HGS Antibody catalog # A01174. Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.