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Product details

Anti-TXN Antibody (C-term)

Catalog number A01219-80ul

Price for A01219-80ul

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Size / count 80 µL

About this product

Boster Bio Anti-TXN Antibody (C-term) (Catalog # A01219) . Tested in IHC-P, WB application (s) . This antibody reacts with Human.

Specifications

Catalog number
A01219-80ul
Size / count
80 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55) .
Synonyms
Thioredoxin, Trx, ATL-derived factor, ADF, Surface-associated sulphydryl protein, SASP, TXN, TRDX, TRX, TRX1
Gene Name
TXN
UniProt
P10599
Host
Rabbit
Reactivity
Human
Immunogen
This TXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the C-terminal region of human TXN.
Clonality
Polyclonal
Applications
IHC-P, WB
Field of Research
Cell Biology, Metabolism, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
217649017182577190322341640802017606900910802911118054
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
11737 Da
Subcellular Location
Nucleus. Cytoplasm. Secreted Note=Translocates from the cytoplasm into the nucleus after phorbol 12- myristate 13-acetate induction (PMA) (PubMed:9108029) . Predominantly in the cytoplasm in non irradiated cells (PubMed:11118054) . Radiation induces translocation of TRX from the cytoplasm to the nucleus (PubMed:11118054) . Secreted by a leaderless secretory pathway (PubMed:1332947) .
Prediction Reactivity
Bovine, Mouse, Pig, Rabbit, Rat
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-TXN Antibody (C-term)?

The catalog number for Anti-TXN Antibody (C-term) is A01219-80ul.

What sizes are available for Anti-TXN Antibody (C-term)?

Anti-TXN Antibody (C-term) is available in the following size(s): 80 µL.

Is Anti-TXN Antibody (C-term) in stock?

Anti-TXN Antibody (C-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-TXN Antibody (C-term)?

The safety data sheet for Anti-TXN Antibody (C-term) is available here: https://www.bosterbio.com/msds?sku=A01219.

What is Anti-TXN Antibody (C-term) used for?

Boster Bio Anti-TXN Antibody (C-term) (Catalog # A01219) . Tested in IHC-P, WB application (s) . This antibody reacts with Human.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

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