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Product details

Anti-TXN Antibody (C-term)

Catalog number A01219-400ul

Price for A01219-400ul

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Size / count 400 µL

About this product

Boster Bio Anti-TXN Antibody (C-term) (Catalog # A01219) . Tested in IHC-P, WB application (s) . This antibody reacts with Human.

Specifications

Catalog number
A01219-400ul
Size / count
400 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55) .
Synonyms
Thioredoxin, Trx, ATL-derived factor, ADF, Surface-associated sulphydryl protein, SASP, TXN, TRDX, TRX, TRX1
Gene Name
TXN
UniProt
P10599
Host
Rabbit
Reactivity
Human
Immunogen
This TXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the C-terminal region of human TXN.
Clonality
Polyclonal
Applications
IHC-P, WB
Field of Research
Cell Biology, Metabolism, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
217649017182577190322341640802017606900910802911118054
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
11737 Da
Subcellular Location
Nucleus. Cytoplasm. Secreted Note=Translocates from the cytoplasm into the nucleus after phorbol 12- myristate 13-acetate induction (PMA) (PubMed:9108029) . Predominantly in the cytoplasm in non irradiated cells (PubMed:11118054) . Radiation induces translocation of TRX from the cytoplasm to the nucleus (PubMed:11118054) . Secreted by a leaderless secretory pathway (PubMed:1332947) .
Prediction Reactivity
Bovine, Mouse, Pig, Rabbit, Rat
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-TXN Antibody (C-term)?

The catalog number for Anti-TXN Antibody (C-term) is A01219-400ul.

What sizes are available for Anti-TXN Antibody (C-term)?

Anti-TXN Antibody (C-term) is available in the following size(s): 400 µL.

Is Anti-TXN Antibody (C-term) in stock?

Anti-TXN Antibody (C-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-TXN Antibody (C-term)?

The safety data sheet for Anti-TXN Antibody (C-term) is available here: https://www.bosterbio.com/msds?sku=A01219.

What is Anti-TXN Antibody (C-term) used for?

Boster Bio Anti-TXN Antibody (C-term) (Catalog # A01219) . Tested in IHC-P, WB application (s) . This antibody reacts with Human.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

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