Anti-p57 CDKN1C Antibody

About this product

Boster Bio Anti-p57 CDKN1C Antibody catalog # A01244. Tested in WB, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

A01244

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Cyclin-dependent kinase inhibitor 1C; Cyclin-dependent kinase inhibitor p57; p57Kip2; CDKN1C; KIP2

Gene Name

CDKN1C

UniProt

P49918

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human p57Kip2 around the non-acetylation site of Lys278. AA range:241-290

Tissue Specificity

Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. Expressed in the eye. High levels are seen in the placenta while low levels are seen in the liver. .

Applications

WB, IF, ELISA

Purification

Immunogen affinity purified

Concentration

1 mg/mL

Form

Liquid

Function

Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non- proliferative state throughout life.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

32177 MW

Gene Name Synonym

Cyclin-dependent kinase inhibitor 1C

Subcellular Location

Nucleus .

Isotype

IgG

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.