Product details

Anti-MDC1 Antibody

Catalog number A01252

Price for A01252

Size / count 100 µL

About this product

Boster Bio Anti-MDC1 Antibody catalog # A01252. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human.

Specifications

Catalog number: A01252
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Mediator of DNA damage checkpoint protein 1; Nuclear factor with BRCT domains 1; MDC1; KIAA0170, NFBD1
Gene Name: MDC1
UniProt: Q14676
Host: Rabbit
Reactivity: Human
Immunogen: Recombinant fusion protein of human MDC1 (NP_055456.2) .
Clonality: Polyclonal
Tissue Specificity: Highly expressed in testis.
Applications: WB, IHC, ICC, IF
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration: 1 mg/mL
Form: Liquid
Function: Required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. May serve as a scaffold for the recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage marked by 'Ser-139' phosphorylation of histone H2AFX. Also required for downstream events subsequent to the recruitment of these proteins. These include phosphorylation and activation of the ATM, CHEK1 and CHEK2 kinases, and stabilization of TP53 and apoptosis. ATM and CHEK2 may also be activated independently by a parallel pathway mediated by TP53BP1.
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight: 226666 MW
Gene Name Synonym: Mediator of DNA damage checkpoint protein 1
Subcellular Location: Nucleus
Protein Name: Mediator of DNA damage checkpoint protein 1
Contents: Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-MDC1 Antibody?

The catalog number for Anti-MDC1 Antibody is A01252.

What sizes are available for Anti-MDC1 Antibody?

Anti-MDC1 Antibody is available in the following size(s): 100 µL.

Is Anti-MDC1 Antibody in stock?

Anti-MDC1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-MDC1 Antibody?

The safety data sheet for Anti-MDC1 Antibody is available here: https://www.bosterbio.com/msds?sku=A01252.

What is Anti-MDC1 Antibody used for?

Boster Bio Anti-MDC1 Antibody catalog # A01252. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

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