Anti-CB2 Antibody (C-term)

Catalog number A01307-3-80ul

Price for A01307-3-80ul

Size / count 80 µL

About this product

Boster Bio Anti-CB2 Antibody (C-term) (Catalog # A01307-3) . Tested in WB, IHC-P, Flow Cytometry application (s) . This antibody reacts with Human.

Specifications

Catalog number: A01307-3-80ul
Size / count: 80 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein) -coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors.
Synonyms: Cannabinoid receptor 2, CB-2, CB2, hCB2, CX5, CNR2, CB2A, CB2B
Gene Name: CNR2
UniProt: P34972
Host: Rabbit
Reactivity: Human
Immunogen: This CB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-356 amino acids from the C-terminal region of human CB2.
Clonality: Polyclonal
Tissue Specificity: Preferentially expressed in cells of the immune system with higher expression in B-cells and NK cells (at protein level) . Expressed in skin in suprabasal layers and hair follicles (at protein level) . Highly expressed in tonsil and to a lower extent in spleen, peripheral blood mononuclear cells, and thymus. PubMed:14657172 could not detect expression in normal brain. Expressed in brain by perivascular microglial cells and dorsal root ganglion sensory neurons (at protein level) . Two isoforms are produced by alternative promoter usage and differ only in the 5' UTR: isoform CB2A is observed predominantly in testis with some expression in brain, while isoform CB2B is predominant in spleen and leukocytes
Applications: WB, IHC-P, Flow Cytometry
Field of Research: Neuroscience, Inflammation
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Function: Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis.
Storage Conditions: Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight: 39681 Da
Subcellular Location: Cell membrane; Multi-pass membrane protein. Cell projection, dendrite. Perikaryon Note=Localizes to apical dendrite of pyramidal neurons.
Isotype: Rabbit IgG
Contents: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-CB2 Antibody (C-term)?

The catalog number for Anti-CB2 Antibody (C-term) is A01307-3-80ul.

What sizes are available for Anti-CB2 Antibody (C-term)?

Anti-CB2 Antibody (C-term) is available in the following size(s): 80 µL.

Is Anti-CB2 Antibody (C-term) in stock?

Anti-CB2 Antibody (C-term) is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-CB2 Antibody (C-term)?

The safety data sheet for Anti-CB2 Antibody (C-term) is available here: https://www.bosterbio.com/msds?sku=A01307-3.

What is Anti-CB2 Antibody (C-term) used for?

Boster Bio Anti-CB2 Antibody (C-term) (Catalog # A01307-3) . Tested in WB, IHC-P, Flow Cytometry application (s) . This antibody reacts with Human.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.