Anti-Ctip2 BCL11B Antibody

About this product

Boster Bio Anti-Ctip2 BCL11B Antibody catalog # A01485. Tested in WB, IHC, IF, ICC, ELISA applications. This antibody reacts with Mouse.

Specifications

Catalog number

A01485

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

B-cell lymphoma/leukemia 11B; BCL-11B; B-cell CLL/lymphoma 11B; COUP-TF-interacting protein 2; Radiation-induced tumor suppressor gene 1 protein; hRit1; BCL11B; CTIP2, RIT1

Gene Name

BCL11B

UniProt

Q9C0K0

Host

Rabbit

Reactivity

Mouse

Immunogen

KLH conjugated synthetic peptide derived from human Ctip2 : 331-4630/894

Clonality

Polyclonal

Tissue Specificity

Highly expressed in brain and in malignant T- cell lines derived from patients with adult T-cell leukemia/lymphoma.

Applications

WB, IHC, IF, ICC, ELISA

Purification

ProA affinity purified

Concentration

1 mg/mL

Form

Liquid

Function

Key regulator of both differentiation and survival of T- lymphocytes during thymocyte development in mammals. Essential in controlling the responsiveness of hematopoietic stem cells to chemotactic signals by modulating the expression of the receptors CCR7 and CCR9, which direct the movement of progenitor cells from the bone marrow to the thymus (PubMed:27959755) . Is a regulator of IL2 promoter and enhances IL2 expression in activated CD4 (+) T- lymphocytes (PubMed:16809611) . Tumor-suppressor that represses transcription through direct, TFCOUP2-independent binding to a GC- rich response element (By similarity) . May also function in the P53-signaling pathway (By similarity) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

95519 MW

Gene Name Synonym

B-cell lymphoma/leukemia 11B

Subcellular Location

Nucleus .

Protein Name

B-cell lymphoma/leukemia 11B

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2