Anti-MAP1LC3B Antibody

Catalog number A01524

Price for A01524

Size / count 0.1 mg

About this product

Boster Bio Anti-MAP1LC3B Antibody (Catalog # A01524) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: A01524
Size / count: 0.1 mg
Dry ice: No
Hazardous: No
Discontinued: No
Background: Microtubule-associated proteins (MAPs) regulate microtubule stability and play critical roles in neuronal development and plasticity (1) . MAP1LC3B belongs to the MAP1 LC3 family and it includes 3 different light chains, LC1, LC2 and LC3 (2) . MAP1LC3B is involved in formation of autophagosomal vacuoles (autophagosomes) (3) . It is most abundant in heart, brain, skeletal muscle and testis. MAP1LC3B is essential for autophagy and associated to the autophagosome membranes after processing (4) .
Synonyms: LC3B, ATG8F, MAP1LC3B-a, MAP1A/1BLC3, MAP1ALC3, Autophagy-related protein LC3 B
Gene Name: MAP1LC3B
UniProt: Q9GZQ8
Host: Rabbit
Reactivity: Human, Mouse, Rat
Cross Reactivity: MAP1LC3B antibody is human, mouse and rat reactive. Multiple isoforms MAP1LC3B are known to exist. MAP1LC3B antibody is predicted to not cross-react with MAP1LC3A or MAP1LC3C
Immunogen: MAP1LC3B antibody was raised against an 18 amino acid peptide near the amino terminus of human MAP1LC3B. The immunogen is located within the first 50 amino acids of MAP1LC3B.
Clonality: Polyclonal
Tissue Specificity: Most abundant in heart, brain, skeletal muscle and testis. Little expression observed in liver.
Applications: ELISA, WB, IHC-P, IF
Field of Research: Autophagy
Purification: MAP1LC3B antibody is affinity chromatography purified via peptide column.
Concentration: 1 mg/mL
Form: Liquid
Function: Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes) . Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.
Storage Conditions: Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Observed Molecular Weight: 14688 MW
Gene Name Synonym: Microtubule-associated protein 1 light chain 3 beta
Subcellular Location: Cytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Cytoplasmic vesicle, autophagosome
Prediction Reactivity: Bovine
Protein Name: Microtubule-associated protein 1 light chain 3 beta
Isotype: IgG
Contents: MAP1LC3B antibody is supplied in PBS containing 0.02% sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-MAP1LC3B Antibody?

The catalog number for Anti-MAP1LC3B Antibody is A01524.

What sizes are available for Anti-MAP1LC3B Antibody?

Anti-MAP1LC3B Antibody is available in the following size(s): 0.1 mg.

Is Anti-MAP1LC3B Antibody in stock?

Anti-MAP1LC3B Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-MAP1LC3B Antibody?

The safety data sheet for Anti-MAP1LC3B Antibody is available here: https://www.bosterbio.com/msds?sku=A01524.

What is Anti-MAP1LC3B Antibody used for?

Boster Bio Anti-MAP1LC3B Antibody (Catalog # A01524) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.