Anti-Protein phosphatase 1D PPM1D Antibody — image 1 of 2

Product details

Anti-Protein phosphatase 1D PPM1D Antibody

Catalog number A01576

Price for A01576

Size / count 0.1 mg

About this product

Boster Bio Anti-Protein phosphatase 1D PPM1D Antibody (Catalog # A01576) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: A01576
Size / count: 0.1 mg
Dry ice: No
Hazardous: No
Discontinued: No
Background: Wild-type p53 induced phosphatase 1 (WIP1) / protein phosphatase magnesium-dependent 1 delta (PPM1D), a protein identified in the p53 DNA response pathway, is a member of the PP2C family of serine/threonine protein phosphatases which selectively inactivates p38 MAPK and dephosphorylates the ATM/ATR targets, Chk1 and p53 (1,2) . Studies have shown that it is overexpressed in human cancers and is involved in the regulation of multiple DNA damage signaling pathways (2,3) . PPM1D deletion results in a reduction of T and B cell function and compromised cell division, rendering cells resistant to becoming cancerous and slowing tumor development (4,5) .
Synonyms: Protein phosphatase Mg2+/Mn2+ dependent 1D, p53-induced protein phosphatase 1, PP2C-DELTA, Protein phosphatase 1D, WIP1
Gene Name: PPM1D
UniProt: Q8IVR6
Host: Rabbit
Reactivity: Human, Mouse, Rat
Cross Reactivity: PPM1D antibody is human, mouse and rat reactive. At least two isoforms of PPM1D are known to exist; this antibody will only detect the larger isoform.
Immunogen: PPM1D antibody was raised against an 18 amino acid peptide near the carboxy terminus of human PPM1D. The immunogen is located within the last 50 amino acids of PPM1D.
Clonality: Polyclonal
Applications: ELISA, WB, IHC-P, IF
Field of Research: Cancer, Cell Cycle
Purification: PPM1D antibody is affinity chromatography purified via peptide column.
Concentration: 1 mg/mL
Form: Liquid
Storage Conditions: PPM1D antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Gene Name Synonym: Protein phosphatase Mg2+/Mn2+ dependent 1D
Protein Name: Protein phosphatase Mg2+/Mn2+ dependent 1D
Isotype: IgG
Contents: PPM1D antibody is supplied in PBS containing 0.02% sodium azide.

Frequently Asked Questions

What is the catalog number for Anti-Protein phosphatase 1D PPM1D Antibody?

The catalog number for Anti-Protein phosphatase 1D PPM1D Antibody is A01576.

What sizes are available for Anti-Protein phosphatase 1D PPM1D Antibody?

Anti-Protein phosphatase 1D PPM1D Antibody is available in the following size(s): 0.1 mg.

Is Anti-Protein phosphatase 1D PPM1D Antibody in stock?

Anti-Protein phosphatase 1D PPM1D Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-Protein phosphatase 1D PPM1D Antibody?

The safety data sheet for Anti-Protein phosphatase 1D PPM1D Antibody is available here: https://www.bosterbio.com/msds?sku=A01576.

What is Anti-Protein phosphatase 1D PPM1D Antibody used for?

Boster Bio Anti-Protein phosphatase 1D PPM1D Antibody (Catalog # A01576) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.