Anti-Cullin 4a CUL4A Antibody — image 1 of 2

Product details

Anti-Cullin 4a CUL4A Antibody

Catalog number A01579

Price for A01579

Size / count 100 µL

About this product

Boster Bio Anti-Cullin 4a CUL4A Antibody catalog # A01579. Tested in WB, ICC, IHC, Flow Cytometry applications. This antibody reacts with Human.

Specifications

Catalog number: A01579
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Cullin-4A; CUL-4A; CUL4A
Gene Name: CUL4A
UniProt: Q13619
Host: Rabbit
Reactivity: Human
Immunogen: Recombinant protein
Clonality: Polyclonal
Applications: WB, ICC, IHC, Flow Cytometry
Purification: ProA affinity purified
Concentration: 1 mg/mL
Form: Liquid
Function: Core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. DCX (DET1-COP1) directs ubiquitination of JUN. DCX (DDB2) directs ubiquitination of XPC. DCX (DDB2) ubiquitinates histones H3-H4 and is required for efficient histone deposition during replication-coupled (H3.1) and replication-independent (H3.3) nucleosome assembly, probably by facilitating the transfer of H3 from ASF1A/ASF1B to other chaperones involved in histone deposition. DCX (DTL) plays a role in PCNA-dependent polyubiquitination of CDT1 and MDM2-dependent ubiquitination of TP53 in response to radiation-induced DNA damage and during DNA replication. In association with DDB1 and SKP2 probably is involved in ubiquitination of CDKN1B/p27kip. Is involved in ubiquitination of HOXA9. DCX (DTL) directs autoubiquitination of DTL.
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight: 87680 MW
Gene Name Synonym: Cullin-4A
Protein Name: Cullin-4A
Contents: Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-Cullin 4a CUL4A Antibody?

The catalog number for Anti-Cullin 4a CUL4A Antibody is A01579.

What sizes are available for Anti-Cullin 4a CUL4A Antibody?

Anti-Cullin 4a CUL4A Antibody is available in the following size(s): 100 µL.

Is Anti-Cullin 4a CUL4A Antibody in stock?

Anti-Cullin 4a CUL4A Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-Cullin 4a CUL4A Antibody?

The safety data sheet for Anti-Cullin 4a CUL4A Antibody is available here: https://www.bosterbio.com/msds?sku=A01579.

What is Anti-Cullin 4a CUL4A Antibody used for?

Boster Bio Anti-Cullin 4a CUL4A Antibody catalog # A01579. Tested in WB, ICC, IHC, Flow Cytometry applications. This antibody reacts with Human.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.