Product details

Anti-GDF-15 Antibody

Catalog number A01583

Price for A01583

Size / count 100 µL

About this product

Boster Bio Anti-GDF-15 Antibody catalog # A01583. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: A01583
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Growth/differentiation factor 15 ; GDF-15 ; Macrophage inhibitory cytokine 1 ; MIC-1
Gene Name: GDF15
UniProt: Q99988
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant fusion protein of human GDF15 (NP_004855.2) .
Clonality: Polyclonal
Tissue Specificity: Highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney (PubMed:9348093) . Detected in plasma (at protein level) (PubMed:28572090, PubMed:29046435) .
Applications: WB, IHC, ICC, IF, IP
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration: 1 mg/mL
Form: Liquid
Function: Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099, PubMed:23468844, PubMed:29046435) . Binds to its receptor, GFRAL, and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099) . It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which contitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions (PubMed:28953886) . On hepatocytes, inhibits growth hormone signaling (By similarity) .
Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight: 34140 MW
Gene Name Synonym: Growth/differentiation factor 15
Subcellular Location: Secreted
Protein Name: Growth/differentiation factor 15
Contents: Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Frequently Asked Questions

What is the catalog number for Anti-GDF-15 Antibody?

The catalog number for Anti-GDF-15 Antibody is A01583.

What sizes are available for Anti-GDF-15 Antibody?

Anti-GDF-15 Antibody is available in the following size(s): 100 µL.

Is Anti-GDF-15 Antibody in stock?

Anti-GDF-15 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-GDF-15 Antibody?

The safety data sheet for Anti-GDF-15 Antibody is available here: https://www.bosterbio.com/msds?sku=A01583.

What is Anti-GDF-15 Antibody used for?

Boster Bio Anti-GDF-15 Antibody catalog # A01583. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.