Anti-40S ribosomal protein SA RPSA Antibody

About this product

Boster Bio Anti-40S ribosomal protein SA RPSA Antibody (Catalog # A01691) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.

Specifications

Catalog number

A01691

Size / count

0.1 mg

Dry ice

No

Hazardous

No

Discontinued

No

Background

The 40S ribosomal protein SA (RPSA) is a high-affinity, non-integrin family, laminin receptor, also known as 67 kDa laminin receptor or 37 kDa laminin receptor precursor (37LRP) (1) . Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes and have been implicated in a variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis (2) . RPSA is overexpressed in multiple types of cancers and has recently been shown to act as a cancer-specific death receptor (3) .

Synonyms

SA, LBP, LRP, p40, 67LR, ICAS, lamR, 37LRP, LAMBR, LAMR1, LRP/LR, LBP/p40, NEM/1CHD4, 40S ribosomal protein SA, 37 kDa laminin receptor precursor

Gene Name

RPSA

UniProt

P08865

Host

Rabbit

Reactivity

Human, Mouse

Cross Reactivity

RPSA antibody is human, mouse and rat reactive.

Immunogen

RPSA antibody was raised against a 17 amino acid peptide near the carboxy terminus of human RPSA. The immunogen is located within amino acids 190 - 240 of RPSA.

Clonality

Polyclonal

Applications

ELISA, WB, IHC-P, IF

Field of Research

Signal Transduction

Purification

RPSA antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA.

Storage Conditions

RPSA antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Observed Molecular Weight

32854 MW

Gene Name Synonym

Ribosomal protein SA

Subcellular Location

Cell membrane. Cytoplasm. Nucleus

Prediction Reactivity

Pig, Bovine, Chicken, Rat, Sheep

Protein Name

Ribosomal protein SA

Isotype

IgG

Contents

RPSA antibody is supplied in PBS containing 0.02% sodium azide.