Anti-CYP4F2 Antibody

About this product

Boster Bio Anti-CYP4F2 Antibody catalog # A01737. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human.

Specifications

Catalog number

A01737

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Phylloquinone omega-hydroxylase CYP4F2 ;1.14.13.194 ;20-hydroxyeicosatetraenoic acid synthase ;20-HETE synthase ;1.14.13.- ; Arachidonic acid omega-hydroxylase ; CYPIVF2; Cytochrome P450 4F2; Cytochrome P450-LTB-omega; Leukotriene-B (4) 20-monooxygenase 1; Leukotriene-B (4) omega-hydroxylase 1 ;1.14.13.30 ; CYP4F2

Gene Name

CYP4F2

UniProt

P78329

Host

Rabbit

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human CYP4F2. AA range:41-90

Tissue Specificity

Liver. Also present in kidney: specifically expressed in the S2 and S3 segments of proximal tubules in cortex and outer medulla (PubMed:10660572) . .

Applications

WB, IHC, IF, ELISA

Purification

Immunogen affinity purified

Concentration

1 mg/mL

Form

Liquid

Function

Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1 (phylloquinone), and menaquinone-4 (MK-4), a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation (PubMed:19297519, PubMed:24138531) . Also shows arachidonic acid omega-hydroxylase activity in kidney, by mediating conversion of arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE), possibly influencing blood pressure control (PubMed:10660572, PubMed:17341693, PubMed:18574070) . Also acts as a leukotriene-B (4) omega-hydroxylase by mediating conversion of leukotriene-B (4) (LTB4) to its omega-hydroxylated metabolite 20-hydroxyleukotriene- B (4) (20-OH LTB4) (PubMed:8026587, PubMed:9799565) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

59853 MW

Gene Name Synonym

Phylloquinone omega-hydroxylase CYP4F2

Subcellular Location

Microsome membrane ; Peripheral membrane protein . Endoplasmic reticulum membrane ; Peripheral membrane protein .

Isotype

IgG

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.