Anti-Transcription factor E3 TFE3 Antibody

About this product

Boster Bio Anti-Transcription factor E3 TFE3 Antibody catalog # A01791. Tested in WB, IHC, ICC applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

A01791

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Transcription factor E3; Class E basic helix-loop-helix protein 33; bHLHe33; TFE3; BHLHE33

Gene Name

TFE3

UniProt

P19532

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 133-178 of Human TFE3.

Clonality

Polyclonal

Tissue Specificity

Ubiquitous in fetal and adult tissues.

Applications

WB, IHC, ICC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3') . Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T- cell-dependent antibody responses in activated CD4 (+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

61521 MW

Gene Name Synonym

Transcription factor E3

Subcellular Location

Nucleus.

Protein Name

Transcription factor E3

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2